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"From Medprompt to o1: Exploration of Run-Time Strategies for Medical Challenge Problems and Beyond"

Generated below podcast on this paper with Google's Illuminate.

o1-preview brings built-in reasoning to medical diagnosis, outperforming traditional prompting methods.

OpenAI's o1-preview model demonstrates superior performance on medical challenges without complex prompting techniques, outperforming GPT-4 with Medprompt across various benchmarks.

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https://arxiv.org/abs/2411.03590

Original Problem 🤔:

→ Traditional LLMs require extensive prompt engineering and run-time strategies like Medprompt to perform well on specialized medical tasks. This increases complexity and computational costs.

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Solution in this Paper 🔧:

→ The paper evaluates OpenAI's o1-preview model, which has built-in reasoning capabilities through reinforcement learning training.

→ The model inherently performs step-by-step problem-solving during inference without needing explicit chain-of-thought prompting.

→ It dynamically allocates computational resources during inference for better results on challenging problems.

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Key Insights 💡:

→ Few-shot prompting actually hinders o1-preview's performance, suggesting in-context learning isn't effective for reasoning-native models

→ Ensembling remains valuable but requires careful cost-performance optimization

→ The model achieves near-saturation on existing medical benchmarks, indicating need for more challenging evaluation metrics

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Results 📊:

→ o1-preview scored 96.0% on MedQA vs 90.2% for GPT-4 with Medprompt

→ Achieved 98.2% accuracy on JMLE-2024, a new Japanese medical licensing exam benchmark

→ Performance scales with reasoning tokens - more reasoning time leads to better accuracy

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